Molecular biology of gram-negative bacterial lipopolysaccharides
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Molecular biology of gram-negative bacterial lipopolysaccharides

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Published by The Academy in New York .
Written in English


  • Lipids.,
  • Polysaccharides.,
  • Molecular biology.

Book details:

Edition Notes

Statementconsulting editor, A. Nowotny ; authors, G.A. Adams [et al.]
SeriesAnnals of the New York Academy of Sciences -- v. 133, art.2., Annals of the New York Academy of Sciences -- v. 133, no. 2.
ContributionsNowotny, A. 1922-
The Physical Object
Paginationp.[277]-786 :
Number of Pages786
ID Numbers
Open LibraryOL15446845M

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Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.. The term lipooligosaccharide ("LOS") is used to refer to a low-molecular-weight form of bacterial . Buy Microbial Toxins: Methods and Protocols (Methods in Molecular Biology) (cyano) bacterial and mold fungus toxins, and a specific focus on Gram-negative endotoxins (lipopolysaccharides). and polysaccharide regions of bacterial : Otto Holst. Lipopolysaccharides in gram-negative bacteria are composed of different parts; lipid A (the hydrophobic portion, and main virulent factor), O-antigen and core oligosaccharide (core OS). Results obtained by Nakao et al. using a mutant Escherichia coli 14 indicate that another component of the LPS, LPS-core-OS, could affect biofilm formation and. Galanos C, Lüderitz O, Rietschel ETh & Westphal O () Newer aspects of the chemistry and biology of bacterial lipopolysaccharides, with special reference to their lipid A component. In: Goodwin TW (ed) International review of biochemistry, biochemistry of lipids vol. 14II. University Park Press, Baltimore pp – Google ScholarCited by:

The last section is devoted to studies on the role of bacterial toxic products in pathogenesis. Bacterial lipopolysaccharides (endotoxins) and exotoxins are described. This book should be of interest to molecular biologists, physiologists, clinical specialists, pathologists, and geneticists.   The use of mutants of Salmonella typhimurium in which biosynthesis of specific lipopolysaccharide precursors is blocked has made possible both biosynthetic studies and structural analyses which provide the basis for the structure of the core polysaccharide shown in Fig. 6. The simplest mutant, which is unable to synthesize UDP-glucose, forms only the Cited by: Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Pasteurellaceae comprise a large and diverse family of Gram-negative bacteria, with members ranging from important pathogens such as Haemophilus influenzae to commensals of the animal and human mucosa. Information on the biology of these organisms has mushroomed in recent years, driven by the development of novel genetic and molecular.

  Hicks, R , Preparation of membrane models of gram-negative bacteria and their interaction with antimicrobial peptides studied by CD and NMR. in Methods in Molecular Biology. Methods in Molecular Biology, vol. , Humana Press Inc., pp. Author: Rickey Hicks. The ability of AGP to bind circulating lipopolysaccharide (LPS) in plasma is believed to help reduce the proinflammatory effect of bacterial lipid A molecules. Here, for the first time we have characterized human AGP binding characteristics of the LPS from a number of pathogenic Gram-negative bacteria: Escherichia coli, Salmonella typhimurium, Klebsiella Cited by: This second edition volume expands on the previous editions with detailed protocols on (cyano) bacterial and mold fungus toxins, and a specific focus on Gram-negative endotoxins (lipopolysaccharides). The chapters in Microbial Toxins: Methods and Protocols, Second Edition present techniques that.   Molecular Basis of Bacterial Pathogenesis focuses on the molecular mechanism of disease associated with bacterial pathogens. Topics covered include the population genetics of bacterial pathogenesis; environmental modulation of gene expression in gram-negative pathogens; and bacterial invasion and intracellular Edition: 1.